Abstract: Background: The tropical climate in Indonesia can potentially predispose to various diseases caused by mosquitoes, one of which is Dengue Hemorrhagic Fever (DHF). Prevention by eradication of mosquito larvae (with larvicide) and mosquito bites (with repellent) is a strategic countermeasure to control DHF disease vectors. Larvicide and synthetic repellent use also can cause the development of resistance against the larvicide and thereby hurt humans. Therefore, it is necessary to find natural alternatives that are safe and more effective. One plant that has potential as
a natural larvicide and repellent is the cat's whisker white-purple variety (Orthosiphon aristatus). The main secondary metabolite groups in white-purple cat whiskers are flavonoids and phenolics,
and both groups are thought to have potential as larvicide and repellent.